STRING 9.05 
  USP9Y protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
USP9Y
ubiquitin specific peptidase 9, Y-linked; May function as a ubiquitin-protein or polyubiquitin hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Monoubiquitination of SMAD4 hampers its ability to form a stable complex w [...] (2555 aa)
(Homo sapiens)
Predicted Functional Partners:
UTY
ubiquitously transcribed tetratricopeptide repeat gene, Y-linked; Histone demethylase (By simil [...] (1347 aa)
      0.990
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; Probable ATP-dependent RNA helicase. May pl [...] (660 aa)
      0.976
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked; Seems to be required for maximal rate of [...] (144 aa)
      0.966
RPS4Y1
ribosomal protein S4, Y-linked 1 (263 aa)
      0.958
ZFY
zinc finger protein, Y-linked; Probable transcriptional activator (801 aa)
      0.957
KDM5D
lysine (K)-specific demethylase 5D; Histone demethylase that specifically demethylates 'Lys- 4' [...] (1539 aa)
      0.954
CYorf15B
chromosome Y open reading frame 15B (181 aa)
      0.946
PRKY
protein kinase, Y-linked (277 aa)
      0.914
TMSB4Y
thymosin beta 4, Y-linked; Plays an important role in the organization of the cytoskeleton. Bin [...] (44 aa)
      0.903
NLGN4Y
neuroligin 4, Y-linked; Putative neuronal cell surface protein involved in cell- cell-interacti [...] (816 aa)
      0.880
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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