STRING 9.05 
  OTX2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
OTX2
orthodenticle homeobox 2; Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS)- 5'-TCTAATCCC-3' (297 aa)
(Homo sapiens)
Predicted Functional Partners:
FOXA2
forkhead box A2; Transcription activator for a number of liver genes such as AFP, albumin, tyro [...] (463 aa)
      0.983
FOXM1
forkhead box M1; Transcriptional activatory factor. May play a role in the control of cell prol [...] (801 aa)
       0.897
NRL
neural retina leucine zipper; Transcription factor which regulates the expression of several ro [...] (237 aa)
       0.874
FGF1
fibroblast growth factor 1 (acidic); The heparin-binding growth factors are angiogenic agents i [...] (155 aa)
       0.867
EFNA2
ephrin-A2 (213 aa)
       0.854
FGF2
fibroblast growth factor 2 (basic); The heparin-binding growth factors are angiogenic agents in [...] (288 aa)
       0.833
DCT
dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); Involved in re [...] (552 aa)
       0.824
WNT5A
wingless-type MMTV integration site family, member 5A; Ligand for members of the frizzled famil [...] (380 aa)
       0.814
YY1
YY1 transcription factor; Multifunctional transcription factor that exhibits positive and negat [...] (414 aa)
       0.811
SIX3
SIX homeobox 3; May be involved in visual system development (332 aa)
       0.750
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (23%)
Permalink