STRING 9.05 
  DOK7 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DOK7
docking protein 7; Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK (By similarity) (504 aa)
(Homo sapiens)
Predicted Functional Partners:
MUSK
muscle, skeletal, receptor tyrosine kinase; Receptor tyrosine kinase that is a key mediator of [...] (869 aa)
      0.975
RAPSN
receptor-associated protein of the synapse; Thought to play some role in anchoring or stabilizi [...] (412 aa)
       0.790
AGRN
agrin; Component of the basal lamina that causes the aggregation of acetylcholine receptors and [...] (2045 aa)
       0.782
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; An [...] (455 aa)
       0.675
ACHE
acetylcholinesterase (Yt blood group); Terminates signal transduction at the neuromuscular junc [...] (617 aa)
       0.675
BCHE
butyrylcholinesterase (602 aa)
       0.675
FLAD1
FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae); Catalyzes the adenylation [...] (587 aa)
       0.571
ABL2
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene); Regulates c [...] (1182 aa)
       0.569
BCS1L
BCS1-like (yeast); Chaperone necessary for the assembly of mitochondrial respiratory chain comp [...] (419 aa)
       0.567
CHRNE
cholinergic receptor, nicotinic, epsilon; After binding acetylcholine, the AChR responds by an [...] (493 aa)
       0.543
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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