STRING 9.05 
  NF2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
NF2
neurofibromin 2 (merlin); Probably acts as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity (595 aa)
(Homo sapiens)
Predicted Functional Partners:
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal [...] (777 aa)
      0.988
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1; Scaffold protein tha [...] (358 aa)
      0.978
CD44
CD44 molecule (Indian blood group); Receptor for hyaluronic acid (HA). Mediates cell-cell and c [...] (742 aa)
      0.976
AKT1
v-akt murine thymoma viral oncogene homolog 1; General protein kinase capable of phosphorylatin [...] (480 aa)
      0.946
SPTBN1
spectrin, beta, non-erythrocytic 1; Fodrin, which seems to be involved in secretion, interacts [...] (2364 aa)
      0.941
SGSM3
small G protein signaling modulator 3; May play a cooperative role in NF2-mediated growth suppr [...] (749 aa)
      0.940
PXN
paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion [...] (591 aa)
      0.938
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta; Type II regulatory chains mediate me [...] (418 aa)
       0.937
MAP3K11
mitogen-activated protein kinase kinase kinase 11; Activates the JUN N-terminal pathway. Requir [...] (847 aa)
      0.931
TSC1
tuberous sclerosis 1; In complex with TSC2, inhibits the nutrient-mediated or growth factor-sti [...] (1164 aa)
      0.891
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (23%)
Permalink