STRING 9.05 
  KCNJ11 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11; This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity) (390 aa)
(Homo sapiens)
Predicted Functional Partners:
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8; Putative subunit of the beta-cell ATP- [...] (1581 aa)
     0.999
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8; This potassium channel is control [...] (424 aa)
   0.984
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Subunit of ATP-sensitive potassium cha [...] (1549 aa)
     0.980
FOXA2
forkhead box A2; Transcription activator for a number of liver genes such as AFP, albumin, tyro [...] (463 aa)
      0.932
PRKACG
protein kinase, cAMP-dependent, catalytic, gamma; Phosphorylates a large number of substrates i [...] (351 aa)
       0.899
ISL1
ISL LIM homeobox 1; Binds to one of the cis-acting domain of the insulin gene enhancer (349 aa)
       0.852
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12; Catalyzes the transformation of estrone (E1) into es [...] (312 aa)
       0.851
GAPDH
glyceraldehyde-3-phosphate dehydrogenase; Independent of its glycolytic activity it is also inv [...] (335 aa)
       0.844
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit; Voltage-sensitive calcium channel [...] (2186 aa)
      0.842
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit; Voltage-sensitive calcium channel [...] (2377 aa)
      0.825
 
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Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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