STRING 9.05 
  HTT protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
HTT
huntingtin; May play a role in microtubule-mediated transport or vesicle function (3142 aa)
(Homo sapiens)
Predicted Functional Partners:
HIP1
huntingtin interacting protein 1; Plays a role in clathrin-mediated endocytosis and trafficking [...] (1037 aa)
     0.997
UBC
ubiquitin C (685 aa)
      0.997
HAP1
huntingtin-associated protein 1; Associates specifically with huntingtin. This binding is enhan [...] (619 aa)
      0.995
ZDHHC17
zinc finger, DHHC-type containing 17; Palmitoyltransferase specific for a subset of neuronal pr [...] (632 aa)
      0.993
CREBBP
CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)
      0.992
GAPDH
glyceraldehyde-3-phosphate dehydrogenase; Independent of its glycolytic activity it is also inv [...] (335 aa)
      0.985
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae); Binds to WASL/N-WASP and suppres [...] (930 aa)
      0.984
PACSIN1
protein kinase C and casein kinase substrate in neurons 1; May play a role in vesicle formation [...] (444 aa)
      0.977
OPTN
optineurin; Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-a [...] (577 aa)
      0.976
SH3GL3
SH3-domain GRB2-like 3; Implicated in endocytosis. May recruit other proteins to membranes with [...] (347 aa)
      0.969
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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