STRING 9.05 
  BLM protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
BLM
Bloom syndrome, RecQ helicase-like; Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (1417 aa)
(Homo sapiens)
Predicted Functional Partners:
RMI1
RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae); Essential component of the R [...] (625 aa)
    0.999
TOP3A
topoisomerase (DNA) III alpha; Reduces the number of supercoils in a highly negatively supercoi [...] (1001 aa)
     0.999
MLH1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); Heterodimerizes with PMS2 to form [...] (756 aa)
    0.999
RAD51
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae); May participate in a common DNA damage r [...] (339 aa)
    0.998
FANCA
Fanconi anemia, complementation group A; DNA repair protein that may operate in a postreplicati [...] (1455 aa)
    0.997
RPA1
replication protein A1, 70kDa; Plays an essential role in several cellular processes in DNA met [...] (616 aa)
     0.997
ERCC6L
excision repair cross-complementing rodent repair deficiency, complementation group 6-like; DNA [...] (1250 aa)
     0.995
FANCM
Fanconi anemia, complementation group M; ATPase required for FANCD2 ubiquitination, a key react [...] (2048 aa)
     0.994
TERF2
telomeric repeat binding factor 2; Binds the telomeric double-stranded TTAGGG repeat. Protects [...] (500 aa)
     0.992
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
      0.992
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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