STRING 9.05 
  ERCC5 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ERCC5
excision repair cross-complementing rodent repair deficiency, complementation group 5; Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too (1186 aa)
(Homo sapiens)
Predicted Functional Partners:
ERCC3
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderm [...] (782 aa)
     0.997
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes [...] (323 aa)
     0.996
CKN2
excision repair cross-complementing rodent repair deficiency, complementation group 6; Is invol [...] (1493 aa)
     0.995
ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2; ATP-depe [...] (760 aa)
     0.994
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa; Component of the core-TFIIH basal trans [...] (548 aa)
     0.988
PCNA
proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delt [...] (261 aa)
      0.988
XPA
xeroderma pigmentosum, complementation group A; Involved in DNA excision repair. Initiates repa [...] (273 aa)
      0.985
ERCC4
excision repair cross-complementing rodent repair deficiency, complementation group 4; Structur [...] (916 aa)
     0.984
XPC
xeroderma pigmentosum, complementation group C; Involved in DNA excision repair. May play a par [...] (940 aa)
      0.984
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; DNA-dependent RNA polymerase catalyze [...] (1970 aa)
      0.982
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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