STRING 9.05 
  SERPINA1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin (418 aa)
(Homo sapiens)
Predicted Functional Partners:
elastase, neutrophil expressed; Modifies the functions of natural killer cells, monocytes and g [...] (267 aa)
transforming growth factor, beta 1; Multifunctional protein that controls proliferation, differ [...] (390 aa)
alpha-2-macroglobulin; Is able to inhibit all four classes of proteinases by a unique 'trapping [...] (1474 aa)
kallikrein-related peptidase 3; Hydrolyzes semenogelin-1 thus leading to the liquefaction of th [...] (261 aa)
MIS12, MIND kinetochore complex component, homolog (S. pombe); Part of the MIS12 complex which [...] (205 aa)
albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2 [...] (609 aa)
plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a [...] (810 aa)
fibronectin 1; Fibronectins bind cell surfaces and various compounds including collagen, fibrin [...] (2477 aa)
TIMP metallopeptidase inhibitor 1; Complexes with metalloproteinases (such as collagenases) and [...] (207 aa)
kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an impor [...] (644 aa)
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