STRING 9.05 
  STAT4 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
STAT4
signal transducer and activator of transcription 4; Carries out a dual function- signal transduction and activation of transcription. Involved in IL12 signaling (748 aa)
(Homo sapiens)
Predicted Functional Partners:
IL12RB2
interleukin 12 receptor, beta 2; Receptor for interleukin-12. This subunit is the signaling com [...] (862 aa)
     0.993
PIAS2
protein inhibitor of activated STAT, 2; Functions as an E3-type small ubiquitin-like modifier ( [...] (621 aa)
     0.992
IRF1
interferon regulatory factor 1; Specifically binds to the upstream regulatory region of type I [...] (325 aa)
      0.985
IL12RB1
interleukin 12 receptor, beta 1; Functions as an interleukin receptor which binds interleukin-1 [...] (381 aa)
     0.982
JUN
jun oncogene; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'- [...] (331 aa)
     0.965
CREBBP
CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)
     0.963
MAPK14
mitogen-activated protein kinase 14; Responds to activation by environmental stress, pro- infla [...] (360 aa)
     0.963
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor); Transcription [...] (770 aa)
    0.961
TYK2
tyrosine kinase 2; Probably involved in intracellular signal transduction by being involved in [...] (1187 aa)
      0.955
IFNG
interferon, gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamm [...] (166 aa)
      0.954
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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