STRING 9.05 
  SPINK5 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SPINK5
serine peptidase inhibitor, Kazal type 5; Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia (1094 aa)
(Homo sapiens)
Predicted Functional Partners:
ST14
suppression of tumorigenicity 14 (colon carcinoma); Degrades extracellular matrix. Proposed to [...] (855 aa)
       0.778
FLG
filaggrin; Aggregates keratin intermediate filaments and promotes disulfide-bond formation amon [...] (4061 aa)
       0.675
KLK5
kallikrein-related peptidase 5; May be involved in desquamation (293 aa)
       0.675
LPA
lipoprotein, Lp(a); Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine pro [...] (2040 aa)
       0.669
DSG1
desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of pl [...] (1049 aa)
       0.653
KLK7
kallikrein-related peptidase 7; May catalyze the degradation of intercellular cohesive structur [...] (253 aa)
       0.651
CETP
cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl e [...] (493 aa)
       0.643
PRSS1
protease, serine, 2 (trypsin 2); Has activity against the synthetic substrates Boc-Phe- Ser-Arg [...] (247 aa)
       0.621
PLTP
phospholipid transfer protein; Converts HDL into larger and smaller particles. May play a key r [...] (493 aa)
       0.613
CXCL14
chemokine (C-X-C motif) ligand 14; Not chemotactive for T-cells, B-cells, monocytes, natural ki [...] (111 aa)
       0.609
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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