STRING 9.05 
  HLA-DR15 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
HLA-DR15
HLA class II histocompatibility antigen, DRB1-15 beta chain Precursor (MHC class I antigen DRB1*15)(DW2.2/DR2.2) (266 aa)
(Homo sapiens)
Predicted Functional Partners:
CD4
CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regul [...] (458 aa)
     0.998
IFNG
interferon, gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamm [...] (166 aa)
      0.985
MLRW
major histocompatibility complex, class II, DR alpha precursor (254 aa)
    0.980
DMA
HLA class II histocompatibility antigen, DM alpha chain Precursor (MHC class II antigen DMA); P [...] (261 aa)
    0.935
CD80
CD80 molecule; Involved in the costimulatory signal essential for T- lymphocyte activation. T-c [...] (288 aa)
      0.930
PTPN11
protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cyt [...] (593 aa)
      0.929
CIITA
class II, major histocompatibility complex, transactivator; Essential for transcriptional activ [...] (1130 aa)
      0.927
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain; Plays a critical rol [...] (296 aa)
      0.927
SP100
SP100 nuclear antigen; May play a role in the control of gene expression (885 aa)
      0.926
IRF5
interferon regulatory factor 5 (514 aa)
      0.925
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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