STRING 9.05 
  DCTN1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DCTN1
dynactin 1 (p150, glued homolog, Drosophila); Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein- dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles (1278 aa)
(Homo sapiens)
Predicted Functional Partners:
DCTN2
dynactin 2 (p50); Modulates cytoplasmic dynein binding to an organelle, and plays a role in pro [...] (406 aa)
    0.998
CLIP1
CAP-GLY domain containing linker protein 1; Seems to be a intermediate filament associated prot [...] (1427 aa)
     0.990
DCTN3
dynactin 3 (p22); Together with dynein may be involved in spindle assembly and cytokinesis (186 aa)
    0.988
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1; Cytoplasmic dynein acts as a motor for the intracellular [...] (4646 aa)
   0.984
MAPRE1
microtubule-associated protein, RP/EB family, member 1; May be involved in microtubule polymeri [...] (268 aa)
      0.974
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2; The intermediate chains seem to help dynein bind t [...] (638 aa)
     0.973
SPTBN2
spectrin, beta, non-erythrocytic 2; Probably plays an important role in neuronal membrane skele [...] (2390 aa)
    0.968
DCTN5
dynactin 5 (p25) (182 aa)
      0.965
DYNC2LI1
dynein, cytoplasmic 2, light intermediate chain 1; May function as a motor for intraflagellar r [...] (351 aa)
     0.963
DCTN6
dynactin 6 (190 aa)
      0.963
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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