STRING 9.05 
  DRD2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DRD2
dopamine receptor D2; This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase (443 aa)
(Homo sapiens)
Predicted Functional Partners:
ADCY2
adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (1091 aa)
      0.964
SSTR5
somatostatin receptor 5; Receptor for somatostatin 28 and to a lesser extent for somatostatin-1 [...] (364 aa)
    0.964
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; Guanin [...] (355 aa)
     0.962
POMC
proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol (267 aa)
      0.953
PDYN
prodynorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a r [...] (254 aa)
      0.951
SST
somatostatin; Somatostatin inhibits the release of somatotropin (116 aa)
      0.950
PENK
proenkephalin; Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. The [...] (267 aa)
      0.950
FLNA
filamin A, alpha; Promotes orthogonal branching of actin filaments and links actin filaments to [...] (2647 aa)
      0.946
SLC6A3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Amine transporter. [...] (620 aa)
      0.939
RGS4
regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activ [...] (302 aa)
      0.939
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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