STRING 9.05 
  TLR1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
TLR1
toll-like receptor 1; Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) (786 aa)
(Homo sapiens)
Predicted Functional Partners:
TLR2
toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial l [...] (784 aa)
   0.984
LY96
lymphocyte antigen 96; Cooperates with TLR4 in the innate immune response to bacterial lipopoly [...] (160 aa)
     0.970
HSPD1
heat shock 60kDa protein 1 (chaperonin); Implicated in mitochondrial protein import and macromo [...] (573 aa)
     0.968
TIRAP
toll-interleukin 1 receptor (TIR) domain containing adaptor protein; Adapter involved in the TL [...] (235 aa)
      0.953
HSPA9
heat shock 70kDa protein 9 (mortalin); Implicated in the control of cell proliferation and cell [...] (679 aa)
      0.946
IRAK1
interleukin-1 receptor-associated kinase 1; Binds to the IL-1 type I receptor following IL-1 en [...] (712 aa)
      0.943
IRAK4
interleukin-1 receptor-associated kinase 4; Required for the efficient recruitment of IRAK1 to [...] (460 aa)
      0.942
TLR6
toll-like receptor 6; Participates in the innate immune response to Gram- positive bacteria and [...] (796 aa)
    0.934
MYD88
myeloid differentiation primary response gene (88); Adapter protein involved in the Toll-like r [...] (309 aa)
     0.930
CD14
CD14 molecule; Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial [...] (375 aa)
    0.926
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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