STRING 9.05 
  POU3F3 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
POU3F3
POU class 3 homeobox 3; Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met- mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity) (500 aa)
(Homo sapiens)
Predicted Functional Partners:
SOX10
SRY (sex determining region Y)-box 10; Transcription factor that seems to function synergistica [...] (466 aa)
      0.885
MYT1L
myelin transcription factor 1-like; May function as a panneural transcription factor associated [...] (1184 aa)
       0.778
SOX11
SRY (sex determining region Y)-box 11; Probably important in the developing nervous system. May [...] (441 aa)
      0.768
ASCL1
achaete-scute complex homolog 1 (Drosophila); May play a role at early stages of development of [...] (236 aa)
       0.760
DLL1
delta-like 1 (Drosophila); Acts as a ligand for Notch receptors. Blocks the differentiation of [...] (723 aa)
       0.675
FEV
FEV (ETS oncogene family); Functions as a transcriptional regulator. According to PubMed-176150 [...] (238 aa)
       0.675
SOX8
SRY (sex determining region Y)-box 8; May play a role in central nervous system, limb and facia [...] (446 aa)
      0.662
PQBP1
polyglutamine binding protein 1; May suppress the ability of POU3F2 to transactivate the DRD1 g [...] (265 aa)
      0.640
POU3F4
POU class 3 homeobox 4; Probable transcription factor which exert its primary action widely dur [...] (361 aa)
     0.634
CREBBP
CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)
      0.626
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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