STRING 9.05 
  RYR2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
RYR2
ryanodine receptor 2 (cardiac); Communication between transverse-tubules and sarcoplasmic reticulum. Contraction of cardiac muscle is triggered by release of calcium ions from SR following depolarization of T- tubules (By similarity) (4965 aa)
(Homo sapiens)
Predicted Functional Partners:
FKBP1B
FK506 binding protein 1B, 12.6 kDa; Associates with the ryanodine receptor (RYR-2) in cardiac m [...] (108 aa)
     0.989
AKAP6
A kinase (PRKA) anchor protein 6; Binds to type II regulatory subunits of protein kinase A and [...] (2319 aa)
     0.983
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit; Voltage-sensitive calcium channel [...] (2186 aa)
     0.930
TRDN
triadin; May be involved in anchoring calsequestrin to the junctional sarcoplasmic reticulum an [...] (731 aa)
       0.926
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha; Phosphorylates a large number of substrates i [...] (351 aa)
     0.925
PRKACG
protein kinase, cAMP-dependent, catalytic, gamma; Phosphorylates a large number of substrates i [...] (351 aa)
      0.918
PRKACB
protein kinase, cAMP-dependent, catalytic, beta; Mediates cAMP-dependent signaling triggered by [...] (398 aa)
      0.918
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit; Voltage-sensitive calcium channel [...] (1873 aa)
      0.902
PKD2L1
polycystic kidney disease 2-like 1; May function as a subunit of an ion channel and act as a tr [...] (805 aa)
       0.877
NOS1
nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule wi [...] (1434 aa)
       0.877
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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