STRING 9.05 
  EGLN1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
egl nine homolog 1 (C. elegans); Catalyzes the post-translational formation of 4- hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex (426 aa)
(Homo sapiens)
Predicted Functional Partners:
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); Functi [...] (826 aa)
endothelial PAS domain protein 1; Transcription factor involved in the induction of oxygen regu [...] (870 aa)
osteosarcoma amplified 9, endoplasmic reticulum lectin; Lectin which functions in endoplasmic r [...] (667 aa)
von Hippel-Lindau tumor suppressor; Involved in the ubiquitination and subsequent proteasomal d [...] (213 aa)
hypoxia inducible factor 3, alpha subunit; Involved in adaptive response to hypoxia. Suppresses [...] (669 aa)
egl nine homolog 3 (C. elegans); Catalyzes the post-translational formation of 4- hydroxyprolin [...] (239 aa)
aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) recept [...] (789 aa)
inhibitor of growth family, member 4; Component of the HBO1 complex which has a histone H4- spe [...] (249 aa)
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); SIII, also known as [...] (112 aa)
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B); SIII, also known as [...] (161 aa)
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Active Prediction Methods:
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Co-expression Experiments Databases Textmining
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