STRING 9.05 
  AGT protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. In response to lowered blood pressure, the enzyme renin cleaves angiotensinogen to produce angiotensin-1 (angiotensin 1-10). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2 (angiotensin 1- 8). Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3 (angiotensi [...] (485 aa)
(Homo sapiens)
Predicted Functional Partners:
REN
renin; Renin is a highly specific endopeptidase, whose only known function is to generate angio [...] (406 aa)
      0.999
INS
insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monos [...] (200 aa)
       0.916
AGTR1
angiotensin II receptor, type 1; Receptor for angiotensin II. Mediates its action by associatio [...] (359 aa)
      0.913
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; Converts angiotensin I to angiotens [...] (1306 aa)
       0.912
IL6
interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)
       0.896
PRCP
prolylcarboxypeptidase (angiotensinase C); Cleaves C-terminal amino acids linked to proline in [...] (517 aa)
      0.876
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; Carboxypeptidase which converts ang [...] (805 aa)
      0.875
TGFB1
transforming growth factor, beta 1; Multifunctional protein that controls proliferation, differ [...] (390 aa)
       0.874
AGTR2
angiotensin II receptor, type 2; Receptor for angiotensin II. Cooperates with MTUS1 to inhibit [...] (363 aa)
      0.868
KNG1
kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an impor [...] (644 aa)
     0.846
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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