STRING 9.05 
  PTGS2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity (604 aa)
(Homo sapiens)
Predicted Functional Partners:
ALOX5
arachidonate 5-lipoxygenase; Catalyzes the first step in leukotriene biosynthesis, and thereby [...] (674 aa)
    0.994
JUN
jun oncogene; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'- [...] (331 aa)
     0.992
FOS
FBJ murine osteosarcoma viral oncogene homolog; Nuclear phosphoprotein which forms a tight but [...] (380 aa)
     0.992
MAPK1
mitogen-activated protein kinase 1; Involved in both the initiation and regulation of meiosis, [...] (360 aa)
      0.992
PTGDS
prostaglandin D2 synthase 21kDa (brain); Catalyzes the conversion of PGH2 to PGD2, a prostaglan [...] (190 aa)
      0.991
MAPK14
mitogen-activated protein kinase 14; Responds to activation by environmental stress, pro- infla [...] (360 aa)
      0.989
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1; Metabolizes several precarcinogens, drug [...] (493 aa)
      0.984
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent); Selectively hydrolyzes arachidonyl [...] (749 aa)
     0.980
PTGES
prostaglandin E synthase (152 aa)
      0.977
CAV1
caveolin 1, caveolae protein, 22kDa; May act as a scaffolding protein within caveolar membranes [...] (178 aa)
      0.975
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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