STRING 9.05 
  SERPINC1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1; Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (464 aa)
(Homo sapiens)
Predicted Functional Partners:
F2
coagulation factor II (thrombin); Thrombin, which cleaves bonds after Arg and Lys, converts fib [...] (622 aa)
    0.999
F9
coagulation factor IX; Factor IX is a vitamin K-dependent plasma protein that participates in t [...] (461 aa)
     0.999
F10
coagulation factor X; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin [...] (488 aa)
    0.999
F5
coagulation factor V (proaccelerin, labile factor); Central regulator of hemostasis. It serves [...] (2224 aa)
     0.991
PLAT
plasminogen activator, tissue; Converts the abundant, but inactive, zymogen plasminogen to plas [...] (562 aa)
       0.968
PLG
plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a [...] (810 aa)
     0.949
KCTD10
potassium channel tetramerisation domain containing 10 (313 aa)
       0.925
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3) (863 aa)
       0.923
SELP
selectin P (granule membrane protein 140kDa, antigen CD62); Ca(2+)-dependent receptor for myelo [...] (830 aa)
       0.917
GPC1
glypican 1; Cell surface proteoglycan that bears heparan sulfate (By similarity) (558 aa)
      0.914
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: medium (60%)
Permalink