STRING 9.05 
  F5 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
F5
coagulation factor V (proaccelerin, labile factor); Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin (2224 aa)
(Homo sapiens)
Predicted Functional Partners:
F2
coagulation factor II (thrombin); Thrombin, which cleaves bonds after Arg and Lys, converts fib [...] (622 aa)
    0.999
MMRN1
multimerin 1; Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the st [...] (1228 aa)
     0.997
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1; Most important serine protease in [...] (464 aa)
     0.991
PROC
protein C (inactivator of coagulation factors Va and VIIIa); Protein C is a vitamin K-dependent [...] (461 aa)
     0.990
F10
coagulation factor X; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin [...] (488 aa)
     0.986
PLG
plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a [...] (810 aa)
     0.973
THBD
thrombomodulin; Thrombomodulin is a specific endothelial cell receptor that forms a 1-1 stoichi [...] (575 aa)
      0.973
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; [...] (402 aa)
      0.961
ALB
albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2 [...] (609 aa)
      0.953
PF4
platelet factor 4; Released during platelet aggregation. Neutralizes the anticoagulant effect o [...] (101 aa)
      0.950
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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