STRING 9.05 
  NGF protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
NGF
nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons (241 aa)
(Homo sapiens)
Predicted Functional Partners:
NTRK1
neurotrophic tyrosine kinase, receptor, type 1; Required for high-affinity binding to nerve gro [...] (796 aa)
     0.999
NGFR
nerve growth factor receptor (TNFR superfamily, member 16); Low affinity receptor which can bin [...] (427 aa)
     0.999
TRPV1
transient receptor potential cation channel, subfamily V, member 1; Receptor-activated non-sele [...] (839 aa)
      0.994
CASP3
caspase 3, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases [...] (277 aa)
      0.991
SORT1
sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance recepto [...] (831 aa)
     0.989
SHC1
SHC (Src homology 2 domain containing) transforming protein 1; Signaling adapter that couples a [...] (584 aa)
      0.983
GIPC1
GIPC PDZ domain containing family, member 1; May be involved in G protein-linked signaling (333 aa)
      0.982
PLG
plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a [...] (810 aa)
     0.975
MMP7
matrix metallopeptidase 7 (matrilysin, uterine); Degrades casein, gelatins of types I, III, IV, [...] (267 aa)
     0.967
SORCS3
sortilin-related VPS10 domain containing receptor 3 (1222 aa)
     0.964
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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