STRING 9.05 
  DKC1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DKC1
small nucleolar RNA, H/ACA box 56; Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse t [...] (514 aa)
(Homo sapiens)
Predicted Functional Partners:
GAR1
GAR1 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenan [...] (217 aa)
     0.999
NHP2
NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenan [...] (153 aa)
   0.999
RUVBL1
RuvB-like 1 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA h [...] (456 aa)
    0.995
RUVBL2
RuvB-like 2 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA h [...] (463 aa)
    0.993
NOP10
NOP10 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintena [...] (64 aa)
     0.992
TERT
telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the re [...] (1132 aa)
     0.985
NOP58
NOP58 ribonucleoprotein homolog (yeast); Required for 60S ribosomal subunit biogenesis (By simi [...] (529 aa)
     0.981
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae); Binds to the 5'-stem-loop of U4 s [...] (128 aa)
     0.978
EIF6
eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its [...] (245 aa)
     0.975
NCL
nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found as [...] (710 aa)
     0.972
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Co-expression Experiments Databases Textmining
 
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