STRING 9.05 
  POLH protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
polymerase (DNA directed), eta; DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci (713 aa)
(Homo sapiens)
Predicted Functional Partners:
proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delt [...] (261 aa)
REV1 homolog (S. cerevisiae); Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP [...] (1251 aa)
ubiquitin C (685 aa)
RAD18 homolog (S. cerevisiae); E3 ubiquitin-protein ligase involved in postreplication repair o [...] (495 aa)
polymerase (DNA directed) iota; Error-prone DNA polymerase specifically involved in DNA repair. [...] (740 aa)
ring finger and CHY zinc finger domain containing 1; Mediates E3-dependent ubiquitination and p [...] (261 aa)
ubiquitin-conjugating enzyme E2B (RAD6 homolog); Catalyzes the covalent attachment of ubiquitin [...] (152 aa)
polymerase (DNA directed), delta 1, catalytic subunit 125kDa; Possesses two enzymatic activitie [...] (1107 aa)
REV3-like, catalytic subunit of DNA polymerase zeta (yeast) (3130 aa)
cell adhesion molecule 1; Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manne [...] (442 aa)
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Co-expression Experiments Databases Textmining
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