STRING 9.05 
  HEYL protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
HEYL
hairy/enhancer-of-split related with YRPW motif-like; Downstream effector of Notch signaling which may be required for cardiovascular development (By similarity). Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 (328 aa)
(Homo sapiens)
Predicted Functional Partners:
NOTCH1
Notch homolog 1, translocation-associated (Drosophila); Functions as a receptor for membrane-bo [...] (2555 aa)
      0.958
MAML1
mastermind-like 1 (Drosophila); Acts as a transcriptional coactivator for NOTCH proteins. Has b [...] (1016 aa)
      0.929
HEY2
hairy/enhancer-of-split related with YRPW motif 2; Downstream effector of Notch signaling which [...] (337 aa)
     0.910
SNW1
SNW domain containing 1; Involved in vitamin D-mediated transcription. Can function as a splici [...] (536 aa)
      0.908
HEY1
hairy/enhancer-of-split related with YRPW motif 1; Downstream effector of Notch signaling which [...] (308 aa)
     0.907
KAT2B
K(lysine) acetyltransferase 2B; Functions as a histone acetyltransferase (HAT) to promote trans [...] (832 aa)
      0.904
MAML2
mastermind-like 2 (Drosophila); Acts as a transcriptional coactivator for NOTCH proteins. Has b [...] (1156 aa)
       0.899
MAML3
mastermind-like 3 (Drosophila); Acts as a transcriptional coactivator for NOTCH proteins. Has b [...] (985 aa)
       0.899
EP300
microRNA 1281; Functions as histone acetyltransferase and regulates transcription via chromatin [...] (2414 aa)
       0.899
CREBBP
CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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