STRING 9.05 
  GSN protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GSN
gelsolin (amyloidosis, Finnish type); Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (782 aa)
(Homo sapiens)
Predicted Functional Partners:
CASP3
caspase 3, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases [...] (277 aa)
     0.980
TNIK
TRAF2 and NCK interacting kinase; Serine/threonine kinase that acts as an essential activator o [...] (1360 aa)
      0.970
PLCG1
phospholipase C, gamma 1; PLC-gamma is a major substrate for heparin-binding growth factor 1 (a [...] (1291 aa)
     0.966
APP
amyloid beta (A4) precursor protein; N-APP binds TNFRSF21 triggering caspase activation and deg [...] (770 aa)
     0.966
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide; Phosphorylates PtdIns, PtdIns4P and Pt [...] (1068 aa)
     0.965
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
      0.953
FN1
fibronectin 1; Fibronectins bind cell surfaces and various compounds including collagen, fibrin [...] (2477 aa)
      0.946
TTR
transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstr [...] (147 aa)
      0.943
CST3
cystatin C; As an inhibitor of cysteine proteinases, this protein is thought to serve an import [...] (146 aa)
      0.938
EGFR
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avi [...] (1210 aa)
     0.935
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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