STRING 9.05 
  DES protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DES
desmin; Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures (470 aa)
(Homo sapiens)
Predicted Functional Partners:
NEB
nebulin; This giant muscle protein may be involved in maintaining the structural integrity of s [...] (6669 aa)
     0.998
AURKB
aurora kinase B; May be directly involved in regulating the cleavage of polar spindle microtubu [...] (344 aa)
     0.991
TTN
titin (33421 aa)
      0.973
TPM1
tropomyosin 1 (alpha); Binds to actin filaments in muscle and non-muscle cells. Plays a central [...] (284 aa)
      0.963
TNNT2
troponin T type 2 (cardiac); Troponin T is the tropomyosin-binding subunit of troponin, the thi [...] (295 aa)
      0.962
TNNI3
troponin I type 3 (cardiac); Troponin I is the inhibitory subunit of troponin, the thin filamen [...] (210 aa)
      0.943
MYL2
myosin, light chain 2, regulatory, cardiac, slow (166 aa)
      0.938
MYBPC3
myosin binding protein C, cardiac; Thick filament-associated protein located in the crossbridge [...] (1274 aa)
      0.933
MYBPC2
myosin binding protein C, fast type; Thick filament-associated protein located in the crossbrid [...] (1141 aa)
      0.932
ACTN2
actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety o [...] (894 aa)
      0.932
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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