STRING 9.05 
  MED12 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
MED12
mediator complex subunit 12; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription [...] (2177 aa)
(Homo sapiens)
Predicted Functional Partners:
CDK8
cyclin-dependent kinase 8; Component of the Mediator complex, a coactivator involved in regulat [...] (464 aa)
     0.999
MED1
mediator complex subunit 1; Component of the Mediator complex, a coactivator involved in the re [...] (1581 aa)
     0.994
MED30
mediator complex subunit 30; Component of the Mediator complex, a coactivator involved in the r [...] (178 aa)
     0.986
MED19
mediator complex subunit 19; Component of the Mediator complex, a coactivator involved in the r [...] (194 aa)
     0.982
CCNC
cyclin C; Component of the Mediator complex, a coactivator involved in regulated gene transcrip [...] (283 aa)
     0.981
MED15
mediator complex subunit 15; Component of the Mediator complex, a coactivator involved in the r [...] (788 aa)
     0.979
MED18
mediator complex subunit 18; Component of the Mediator complex, a coactivator involved in the r [...] (208 aa)
     0.978
MED17
mediator complex subunit 17; Component of the Mediator complex, a coactivator involved in the r [...] (651 aa)
     0.977
MED29
mediator complex subunit 29; Component of the Mediator complex, a coactivator involved in the r [...] (221 aa)
     0.971
MED13
mediator complex subunit 13; Component of the Mediator complex, a coactivator involved in the r [...] (2174 aa)
     0.971
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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