STRING 9.05 
  PQBP1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PQBP1
polyglutamine binding protein 1; May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit (265 aa)
(Homo sapiens)
Predicted Functional Partners:
WDR77
WD repeat domain 77; Non-catalytic component of the 20S PRMT5-containing methyltransferase comp [...] (342 aa)
       0.992
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H'); This protein is a component of the heterogeneo [...] (449 aa)
       0.986
AQR
aquarius homolog (mouse); Intron-binding spliceosomal protein required to link pre-mRNA splicin [...] (1485 aa)
       0.974
WBP11
WW domain binding protein 11; May play a role in the regulation of pre-mRNA processing (641 aa)
      0.960
SF3A2
splicing factor 3a, subunit 2, 66kDa; Subunit of the splicing factor SF3A required for 'A' comp [...] (464 aa)
      0.952
ATXN1
ataxin 1; Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polygluta [...] (815 aa)
      0.914
TXNL4A
thioredoxin-like 4A; Essential role in pre-mRNA splicing (142 aa)
      0.906
FTSJ1
FtsJ homolog 1 (E. coli) (329 aa)
      0.849
POU3F2
POU class 3 homeobox 2; Transcription factor that binds preferentially to the recognition seque [...] (443 aa)
      0.767
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa; Accessory subunit of the mitoch [...] (163 aa)
       0.706
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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