STRING 9.05 
  WAS protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia); Effector protein for Rho-type GTPases, providing a link with the Arp2/3 complex that regulates the structure and dynamics of the actin cytoskeleton. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function (502 aa)
(Homo sapiens)
Predicted Functional Partners:
CDC42
cell division cycle 42 (GTP binding protein, 25kDa); Plasma membrane-associated small GTPase wh [...] (191 aa)
     0.999
WIPF1
WAS/WASL interacting protein family, member 1; May have direct activity on the actin cytoskelet [...] (503 aa)
      0.999
FYN
FYN oncogene related to SRC, FGR, YES; Implicated in the control of cell growth. Plays a role i [...] (537 aa)
      0.999
NCK1
NCK adaptor protein 1; Adapter protein which associates with tyrosine- phosphorylated growth fa [...] (377 aa)
     0.998
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1; Involved in regulation of the actin [...] (416 aa)
     0.996
HCK
hemopoietic cell kinase; May serve as part of a signaling pathway coupling the Fc receptor to t [...] (526 aa)
      0.985
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa; Functions as component of the Arp2/3 compl [...] (178 aa)
     0.984
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
      0.984
BTK
Bruton agammaglobulinemia tyrosine kinase; Plays a crucial role in B-cell ontogeny. Transiently [...] (659 aa)
     0.984
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog (529 aa)
     0.982
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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