STRING 9.05 
  FXN protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
FXN
frataxin; Probably involved in iron homeostasis. Anti-apoptotic protein which prevents mitochondrial damage and reactive oxygen species (ROS) production (210 aa)
(Homo sapiens)
Predicted Functional Partners:
IscS
NFS1 nitrogen fixation 1 homolog (S. cerevisiae); Catalyzes the removal of elemental sulfur fro [...] (457 aa)
      0.971
PMPCB
peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitocho [...] (489 aa)
      0.968
LYRM4
LYR motif containing 4; May be involved in mitochondrial iron-sulfur protein biosynthesis (96 aa)
      0.948
HSPA9
heat shock 70kDa protein 9 (mortalin); Implicated in the control of cell proliferation and cell [...] (679 aa)
       0.941
EPAS1
endothelial PAS domain protein 1; Transcription factor involved in the induction of oxygen regu [...] (870 aa)
      0.914
ARNT
aryl hydrocarbon receptor nuclear translocator; Required for activity of the Ah (dioxin) recept [...] (789 aa)
       0.899
EPO
erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocy [...] (193 aa)
       0.854
ISCU
iron-sulfur cluster scaffold homolog (E. coli); Involved in the assembly or repair of the [Fe-S [...] (167 aa)
     0.823
ACO2
aconitase 2, mitochondrial (780 aa)
      0.819
EPOR
erythropoietin receptor; Receptor for erythropoietin. Mediates erythropoietin- induced erythrob [...] (508 aa)
       0.801
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (36%)
Permalink