STRING 9.05 
  CASK protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family); Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1 (921 aa)
(Homo sapiens)
Predicted Functional Partners:
SDC2
syndecan 2; Cell surface proteoglycan that bears heparan sulfate (201 aa)
     0.998
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); Protein 4.1 is a major str [...] (775 aa)
     0.995
TBR1
T-box, brain, 1; Probable transcriptional regulator involved in developmental processes. TBR1 i [...] (682 aa)
      0.995
SDC3
syndecan 3; Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a [...] (442 aa)
     0.994
CASKIN1
CASK interacting protein 1; May link the scaffolding protein CASK to downstream intracellular e [...] (1431 aa)
      0.991
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4; This receptor is controlled by G [...] (445 aa)
      0.991
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1; Putative function in synaptic [...] (837 aa)
      0.988
LIN7A
lin-7 homolog A (C. elegans); Plays a role in establishing and maintaining the asymmetric distr [...] (233 aa)
     0.986
DLG1
discs, large homolog 1 (Drosophila); Essential multidomain scaffolding protein required for nor [...] (926 aa)
     0.980
SDC1
syndecan 1; Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate a [...] (310 aa)
     0.973
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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