STRING 9.05 
  CYBB protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CYBB
cytochrome b-245, beta polypeptide; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc (570 aa)
(Homo sapiens)
Predicted Functional Partners:
NCF2
neutrophil cytosolic factor 2; NCF2, NCF1, and a membrane bound cytochrome b558 are required fo [...] (526 aa)
    0.991
CYBA
cytochrome b-245, alpha polypeptide; Critical component of the membrane-bound oxidase of phagoc [...] (195 aa)
     0.990
NCF4
neutrophil cytosolic factor 4, 40kDa; Component of the NADPH-oxidase, a multicomponent enzyme s [...] (348 aa)
    0.979
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Plasma [...] (211 aa)
     0.972
NCF1
neutrophil cytosolic factor 1; May be required for activation of the latent NADPH oxidase (nece [...] (390 aa)
    0.963
NCF1C
neutrophil cytosolic factor 1C pseudogene; NCF2, NCF1, and a membrane bound cytochrome b558 are [...] (390 aa)
      0.927
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); May play [...] (707 aa)
     0.915
MAPK14
mitogen-activated protein kinase 14; Responds to activation by environmental stress, pro- infla [...] (360 aa)
      0.912
VCAM1
vascular cell adhesion molecule 1; Important in cell-cell recognition. Appears to function in l [...] (739 aa)
      0.910
MAPK11
mitogen-activated protein kinase 11; Kinase involved in a signal transduction pathway that is a [...] (364 aa)
       0.899
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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