STRING 9.05 
  PHEX protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PHEX
phosphate regulating endopeptidase homolog, X-linked; Probably involved in bone and dentin mineralization and renal phosphate reabsorption (749 aa)
(Homo sapiens)
Predicted Functional Partners:
FGF23
fibroblast growth factor 23; Regulator of phosphate homeostasis. Inhibits renal tubular phospha [...] (251 aa)
      0.988
MEPE
matrix extracellular phosphoglycoprotein; Seems to play a role in mineralization (525 aa)
       0.955
PTH
parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing [...] (115 aa)
       0.927
DIF
Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)( [...] (233 aa)
       0.804
CANX
calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the en [...] (592 aa)
       0.800
SLC34A1
solute carrier family 34 (sodium phosphate), member 1; May be involved in actively transporting [...] (639 aa)
       0.718
SMS
spermine synthase; Required for normal viability, growth and fertility (By similarity) (366 aa)
       0.714
SLC34A3
solute carrier family 34 (sodium phosphate), member 3; May be involved in actively transporting [...] (599 aa)
       0.714
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1; Involved primarily in ATP hydrolysis at the [...] (925 aa)
       0.659
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1; Catalyzes the conversion of 25-hydroxyv [...] (508 aa)
       0.655
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (24%)
Permalink