STRING 9.05 
  TFAP2A protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis [...] (437 aa)
(Homo sapiens)
Predicted Functional Partners:
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; Interferes w [...] (270 aa)
      0.982
CASP6
caspase 6, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases [...] (293 aa)
     0.967
YY1
YY1 transcription factor; Multifunctional transcription factor that exhibits positive and negat [...] (414 aa)
      0.943
BCL2
B-cell CLL/lymphoma 2; Suppresses apoptosis in a variety of cell systems including factor-depen [...] (239 aa)
       0.899
SP1
Sp1 transcription factor; Transcription factor that can activate or repress transcription in re [...] (785 aa)
       0.898
UBC
ubiquitin C (685 aa)
       0.897
ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene [...] (1255 aa)
       0.885
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4; Acts as tran [...] (184 aa)
      0.868
VEGFA
vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and [...] (412 aa)
       0.865
YBX1
Y box binding protein 1; Binds to splice sites in pre-mRNA and regulates splice site selection. [...] (324 aa)
      0.860
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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