STRING 9.05 
  VLDLR protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
VLDLR
very low density lipoprotein receptor; Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity) (873 aa)
(Homo sapiens)
Predicted Functional Partners:
RELN
reelin; Extracellular matrix serine protease that plays a role in layering of neurons in the ce [...] (3460 aa)
     0.999
LRPAP1
low density lipoprotein receptor-related protein associated protein 1; Interacts with LRP1/alph [...] (357 aa)
     0.997
DAB1
disabled homolog 1 (Drosophila); Adapter molecule functioning in neural development. May regula [...] (555 aa)
     0.990
APOE
apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particle [...] (317 aa)
      0.988
PLAU
plasminogen activator, urokinase; Specifically cleave the zymogen plasminogen to form the activ [...] (431 aa)
      0.986
FYN
FYN oncogene related to SRC, FGR, YES; Implicated in the control of cell growth. Plays a role i [...] (537 aa)
      0.937
PAFAH1B1
platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa); Required for proper [...] (410 aa)
      0.933
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; [...] (402 aa)
      0.932
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); Integrin alpha-3/beta-1 i [...] (1066 aa)
      0.926
PLAUR
plasminogen activator, urokinase receptor; Acts as a receptor for urokinase plasminogen activat [...] (335 aa)
      0.925
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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