STRING 9.05 
  LRRK1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
LRRK1
leucine-rich repeat kinase 1 (2015 aa)
(Homo sapiens)
Predicted Functional Partners:
GRB2
growth factor receptor-bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)
       0.643
ABL1
c-abl oncogene 1, receptor tyrosine kinase; Regulates cytoskeleton remodeling during cell diffe [...] (1149 aa)
      0.621
BCR
breakpoint cluster region; GTPase-activating protein for RAC1 and CDC42. Promotes the exchange [...] (1271 aa)
       0.621
ALG3
asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae); Adds [...] (438 aa)
       0.450
ADPGK
ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate [...] (496 aa)
       0.425
RIMS1
regulating synaptic membrane exocytosis 1; Rab effector involved in exocytosis. May act as scaf [...] (1692 aa)
       0.422
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1; Nucleoplasmic shuttling pr [...] (985 aa)
       0.416
SAV1
salvador homolog 1 (Drosophila); Potential scaffold protein (383 aa)
       0.414
INTS1
integrator complex subunit 1; Component of the Integrator complex, a complex involved in the sm [...] (2190 aa)
       0.411
SASH1
SAM and SH3 domain containing 1; May have a role in a signaling pathway. Could act as a tumor s [...] (1247 aa)
       0.408
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (20%)
Permalink