STRING 9.05 
  ABCC8 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8; Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release (1581 aa)
(Homo sapiens)
Predicted Functional Partners:
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11; This receptor is controlled by G [...] (390 aa)
     0.999
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8; This potassium channel is control [...] (424 aa)
     0.993
INS
insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monos [...] (200 aa)
       0.946
FOXA2
forkhead box A2; Transcription activator for a number of liver genes such as AFP, albumin, tyro [...] (463 aa)
      0.936
PRKACG
protein kinase, cAMP-dependent, catalytic, gamma; Phosphorylates a large number of substrates i [...] (351 aa)
       0.899
STX1A
syntaxin 1A (brain); Potentially involved in docking of synaptic vesicles at presynaptic active [...] (288 aa)
       0.859
DIF
Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)( [...] (233 aa)
       0.815
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit; Voltage-sensitive calcium channel [...] (2186 aa)
      0.812
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit; Voltage-sensitive calcium channel [...] (2377 aa)
      0.809
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit; Voltage-sensitive calcium channel [...] (2340 aa)
      0.804
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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