STRING 9.05 
  PSAP protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PSAP
prosaposin; The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins- the sphingolipids activator proteins (coproteins) (524 aa)
(Homo sapiens)
Predicted Functional Partners:
CD1B
CD1b molecule; Antigen-presenting protein that binds self and non-self lipid and glycolipid ant [...] (333 aa)
      0.861
SORT1
sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance recepto [...] (831 aa)
       0.859
GBA
glucosidase, beta; acid (includes glucosylceramidase) (536 aa)
      0.842
CTSD
cathepsin D; Acid protease active in intracellular protein breakdown. Involved in the pathogene [...] (412 aa)
     0.837
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis) (747 aa)
       0.800
TFPI2
tissue factor pathway inhibitor 2; May play a role in the regulation of plasmin-mediated matrix [...] (235 aa)
       0.800
MTCH1
mitochondrial carrier homolog 1 (C. elegans); Potential mitochondrial transporter. May play a r [...] (372 aa)
      0.753
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1; Hydrolyzes the sphingolipid ceramide into [...] (411 aa)
      0.714
GALC
galactosylceramidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsph [...] (685 aa)
       0.657
ARSA
arylsulfatase A; Hydrolyzes cerebroside sulfate (507 aa)
       0.657
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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