STRING 9.05 
  DYSF protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
DYSF
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive); Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity) (2119 aa)
(Homo sapiens)
Predicted Functional Partners:
CAPN3
calpain 3, (p94); Calcium-regulated non-lysosomal thiol-protease (821 aa)
      0.978
CAV3
caveolin 3; May act as a scaffolding protein within caveolar membranes. Interacts directly with [...] (151 aa)
      0.971
ANXA2
annexin A2 pseudogene 1; Calcium-regulated membrane-binding protein whose affinity for calcium [...] (357 aa)
      0.941
ANXA1
annexin A1; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved [...] (346 aa)
      0.941
DMD
dystrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (3685 aa)
       0.926
TRIM72
tripartite motif-containing 72; Muscle-specific protein that plays a central role in cell membr [...] (477 aa)
       0.918
AHNAK
AHNAK nucleoprotein; May be required for neuronal cell differentiation (5890 aa)
       0.885
PARVB
parvin, beta; Probably plays a role in the regulation of cell adhesion and cytoskeleton organiz [...] (397 aa)
       0.857
QDPR
quinoid dihydropteridine reductase; The product of this enzyme, tetrahydrobiopterin (BH-4), is [...] (244 aa)
       0.854
TUBA1A
tubulin, alpha 1a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, [...] (451 aa)
       0.805
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (31%)
Permalink