STRING 9.05 
  SCN10A protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SCN10A
sodium channel, voltage-gated, type X, alpha subunit; This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Its electrophysiological properties vary depending on the type of the associated beta subunits (in vitro). Plays a role in neuropathic pain mechanisms (By similarity) (1956 aa)
(Homo sapiens)
Predicted Functional Partners:
SCLT1
sodium channel and clathrin linker 1; Adapter protein that links SCN10A to clathrin. Regulates [...] (688 aa)
      0.910
CALM1
calmodulin 1 (phosphorylase kinase, delta); Calmodulin mediates the control of a large number o [...] (149 aa)
       0.837
CALM3
calmodulin 3 (phosphorylase kinase, delta) (149 aa)
       0.837
CALM2
calmodulin 2 (phosphorylase kinase, delta) (149 aa)
       0.837
NAV1
neuron navigator 1; May be involved in neuronal migration (By similarity) (1874 aa)
       0.750
APP
amyloid beta (A4) precursor protein; N-APP binds TNFRSF21 triggering caspase activation and deg [...] (770 aa)
       0.750
S100A10
S100 calcium binding protein A10; Because S100A10 induces the dimerization of ANXA2/p36, it may [...] (97 aa)
       0.675
ANXA2
annexin A2 pseudogene 1; Calcium-regulated membrane-binding protein whose affinity for calcium [...] (357 aa)
       0.659
ARHGAP24
Rho GTPase activating protein 24; Rho GTPase-activating protein involved in cell polarity, cell [...] (748 aa)
       0.659
ACTB
actin, beta; Actins are highly conserved proteins that are involved in various types of cell mo [...] (375 aa)
      0.627
 
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Co-expression Experiments Databases Textmining
 
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