STRING 9.05 
  PDHA1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (390 aa)
(Homo sapiens)
Predicted Functional Partners:
PDHB
pyruvate dehydrogenase (lipoamide) beta; The pyruvate dehydrogenase complex catalyzes the overa [...] (359 aa)
 0.999
DLAT
dihydrolipoamide S-acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall [...] (647 aa)
  0.998
PDHX
pyruvate dehydrogenase complex, component X; Required for anchoring dihydrolipoamide dehydrogen [...] (501 aa)
  0.997
DLD
dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage [...] (509 aa)
    0.995
PDK3
pyruvate dehydrogenase kinase, isozyme 3; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (415 aa)
    0.992
PDK2
pyruvate dehydrogenase kinase, isozyme 2; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (407 aa)
     0.984
BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide; The branched-chain alpha-keto dehy [...] (392 aa)
  0.980
DBT
dihydrolipoamide branched chain transacylase E2; The branched-chain alpha-keto dehydrogenase co [...] (482 aa)
    0.974
PDK4
pyruvate dehydrogenase kinase, isozyme 4; Inhibits the mitochondrial pyruvate dehydrogenase com [...] (411 aa)
     0.964
PC
pyruvate carboxylase; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-depen [...] (1178 aa)
     0.927
 
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Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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