STRING 9.05 
  SLC46A1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SLC46A1
solute carrier family 46 (folate transporter), member 1; Has been shown to act both as an intestinal proton- coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme (459 aa)
(Homo sapiens)
Predicted Functional Partners:
HMOX1
heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge [...] (288 aa)
      0.937
HMOX2
heme oxygenase (decycling) 2; Heme oxygenase cleaves the heme ring at the alpha methene bridge [...] (316 aa)
      0.910
FOLR1
folate receptor 1 (adult); Binds to folate and reduced folic acid derivatives and mediates deli [...] (257 aa)
       0.641
QDPR
quinoid dihydropteridine reductase; The product of this enzyme, tetrahydrobiopterin (BH-4), is [...] (244 aa)
       0.619
SLC19A1
solute carrier family 19 (folate transporter), member 1; Transporter for the intake of folate. [...] (591 aa)
       0.563
FPGS
folylpolyglutamate synthase; Conversion of folates to polyglutamate derivatives. This allows ti [...] (587 aa)
       0.514
SLC19A3
solute carrier family 19, member 3; Mediates high affinity thiamine uptake, propably via a prot [...] (496 aa)
       0.504
HIAT1
hippocampus abundant transcript 1 (490 aa)
       0.469
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Important [...] (561 aa)
       0.462
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase); Hydrolyzes the polyglut [...] (318 aa)
       0.429
 
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