STRING 9.05 
  HSP72 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
Heat shock 70 kDa protein 1 (HSP70.1)(HSP70-1/HSP70-2); In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection [...] (641 aa)
(Homo sapiens)
Predicted Functional Partners:
heat shock transcription factor 1; DNA-binding protein that specifically binds heat shock promo [...] (529 aa)
heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone. Has ATPase a [...] (854 aa)
nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associate [...] (1247 aa)
interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)
spastic ataxia of Charlevoix-Saguenay (sacsin); May function in chaperone-mediated protein fold [...] (4579 aa)
toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to ba [...] (839 aa)
apoptosis-inducing factor, mitochondrion-associated, 1; Probable oxidoreductase that acts as a [...] (613 aa)
insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monos [...] (200 aa)
mitogen-activated protein kinase kinase 1; Catalyzes the concomitant phosphorylation of a threo [...] (393 aa)
heat shock 60kDa protein 1 (chaperonin); Implicated in mitochondrial protein import and macromo [...] (573 aa)
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
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