STRING 9.05 
  HSP72 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
HSP72
Heat shock 70 kDa protein 1 (HSP70.1)(HSP70-1/HSP70-2); In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection [...] (641 aa)
(Homo sapiens)
Predicted Functional Partners:
HSF1
heat shock transcription factor 1; DNA-binding protein that specifically binds heat shock promo [...] (529 aa)
       0.923
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone. Has ATPase a [...] (854 aa)
     0.916
NID1
nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associate [...] (1247 aa)
      0.902
IL6
interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)
       0.885
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin); May function in chaperone-mediated protein fold [...] (4579 aa)
       0.884
TLR4
toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to ba [...] (839 aa)
       0.874
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1; Probable oxidoreductase that acts as a [...] (613 aa)
       0.870
INS
insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monos [...] (200 aa)
       0.867
MAP2K1
mitogen-activated protein kinase kinase 1; Catalyzes the concomitant phosphorylation of a threo [...] (393 aa)
      0.859
HSPD1
heat shock 60kDa protein 1 (chaperonin); Implicated in mitochondrial protein import and macromo [...] (573 aa)
      0.850
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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