STRING 9.05 
  MRD5 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
MRD5
Ras GTPase-activating protein SynGAP (Synaptic Ras GTPase-activating protein 1)(Synaptic Ras-GAP 1)(Neuronal RasGAP); Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR- mediated miniature excitatory postsynaptic currents. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By simi [...] (1343 aa)
(Homo sapiens)
Predicted Functional Partners:
SMAP1
small ArfGAP 1; GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent [...] (467 aa)
       0.677
DLGAP2
discs, large (Drosophila) homolog-associated protein 2; May play a role in the molecular organi [...] (975 aa)
       0.625
RAB40AL
RAB40A, member RAS oncogene family-like; May be a substrate-recognition component of a SCF-like [...] (278 aa)
       0.621
ARHGAP32
Rho/Cdc42/Rac GTPase-activating protein RICS (p200RhoGAP)(p250GAP)(RhoGAP involved in the beta- [...] (2087 aa)
       0.609
PTCHD1
patched domain containing 1 (888 aa)
       0.607
DDX53
DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 (631 aa)
       0.599
SHANK2
SH3 and multiple ankyrin repeat domains 2; Seems to be an adapter protein in the postsynaptic d [...] (1843 aa)
       0.579
ULK1
unc-51-like kinase 1 (C. elegans); Involved in autophagy. Required for autophagosome formation [...] (1050 aa)
       0.569
PTCH2
patched homolog 2 (Drosophila); May have a role in epidermal development. May act as a receptor [...] (1203 aa)
       0.469
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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