STRING 9.05 
  BDNF protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
BDNF
brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plastic [...] (329 aa)
(Homo sapiens)
Predicted Functional Partners:
NTRK2
neurotrophic tyrosine kinase, receptor, type 2; Receptor for brain-derived neurotrophic factor [...] (838 aa)
     0.999
NGFR
nerve growth factor receptor (TNFR superfamily, member 16); Low affinity receptor which can bin [...] (427 aa)
      0.996
SORT1
sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance recepto [...] (831 aa)
     0.990
NTF3
neurotrophin 3; Seems to promotes the survival of visceral and proprioceptive sensory neurons (270 aa)
     0.963
CREB1
cAMP responsive element binding protein 1; This protein binds the cAMP response element (CRE), [...] (341 aa)
       0.947
GRIK1
glutamate receptor, ionotropic, kainate 1; Ionotropic glutamate receptor. L-glutamate acts as a [...] (918 aa)
       0.947
NOS3
nitric oxide synthase 3 (endothelial cell); Produces nitric oxide (NO) which is implicated in v [...] (1203 aa)
      0.945
CDH2
cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium dependent cell adhesion protei [...] (906 aa)
     0.941
MAPK9
mitogen-activated protein kinase 9; Responds to activation by environmental stress and pro- inf [...] (424 aa)
      0.937
CDC42
cell division cycle 42 (GTP binding protein, 25kDa); Plasma membrane-associated small GTPase wh [...] (191 aa)
      0.937
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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