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Akap17b Akap17b Gm14569 Gm14569 Gtpbp6 Gtpbp6 Sh3rf3 Sh3rf3 Txlng Txlng Mrpl30 Mrpl30 Mitd1 Mitd1 Tmem121 Tmem121 Zfp871 Zfp871 Pglyrp2 Pglyrp2 Nlgn1 Nlgn1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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[Homology]
Score
Akap17bA-kinase anchor protein 17B; Splice factor regulating alternative splice site selection for certain mRNA precursors. (959 aa)    
Predicted Functional Partners:
Gm14569
Acrosomal protein KIAA1210.
      
 0.800
Gtpbp6
Putative GTP-binding protein 6.
   
  
 0.540
Sh3rf3
E3 ubiquitin-protein ligase SH3RF3; Has E3 ubiquitin-protein ligase activity.
      
 0.538
Txlng
Gamma-taxilin; May be involved in intracellular vesicle traffic (By similarity). Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression.
   
  
 0.521
Mrpl30
39S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family.
      
 0.520
Mitd1
MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex.
      
 0.519
Tmem121
Transmembrane protein 121; May play a role in MAPK signaling.
      
 0.519
Zfp871
Zinc finger protein 871.
      
 0.519
Pglyrp2
N-acetylmuramoyl-L-alanine amidase; May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
      
 0.515
Nlgn1
Neuroligin-1; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and [...]
      
 0.477
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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