node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Agr2 | Fcgbp | ENSRNOP00000068828 | ENSRNOP00000053950 | Anterior gradient 2 (Xenopus laevis) (Predicted), isoform CRA_a. | Fc fragment of IgG-binding protein. | 0.613 |
Agr2 | Muc13 | ENSRNOP00000068828 | ENSRNOP00000002444 | Anterior gradient 2 (Xenopus laevis) (Predicted), isoform CRA_a. | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | 0.477 |
Agr2 | Muc6 | ENSRNOP00000068828 | ENSRNOP00000072558 | Anterior gradient 2 (Xenopus laevis) (Predicted), isoform CRA_a. | Mucin 6, oligomeric mucus/gel-forming. | 0.489 |
Agr2 | Tff3 | ENSRNOP00000068828 | ENSRNOP00000060620 | Anterior gradient 2 (Xenopus laevis) (Predicted), isoform CRA_a. | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). | 0.643 |
Cdx1 | Tff3 | ENSRNOP00000071345 | ENSRNOP00000060620 | Homeobox protein CDX-1; Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA. | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). | 0.588 |
Cdx2 | Muc6 | ENSRNOP00000045045 | ENSRNOP00000072558 | Caudal type homeo box 2. | Mucin 6, oligomeric mucus/gel-forming. | 0.510 |
Cdx2 | Tff3 | ENSRNOP00000045045 | ENSRNOP00000060620 | Caudal type homeo box 2. | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). | 0.584 |
Clu | Cst3 | ENSRNOP00000072116 | ENSRNOP00000007175 | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] | Cystatin-C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L; Belongs to the cystatin family. | 0.770 |
Clu | Havcr1 | ENSRNOP00000072116 | ENSRNOP00000009573 | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] | Hepatitis A virus cellular receptor 1 homolog; May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity). | 0.743 |
Clu | Tff3 | ENSRNOP00000072116 | ENSRNOP00000060620 | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). | 0.625 |
Cst3 | Clu | ENSRNOP00000007175 | ENSRNOP00000072116 | Cystatin-C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L; Belongs to the cystatin family. | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] | 0.770 |
Cst3 | Havcr1 | ENSRNOP00000007175 | ENSRNOP00000009573 | Cystatin-C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L; Belongs to the cystatin family. | Hepatitis A virus cellular receptor 1 homolog; May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity). | 0.897 |
Cst3 | Tff3 | ENSRNOP00000007175 | ENSRNOP00000060620 | Cystatin-C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L; Belongs to the cystatin family. | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). | 0.633 |
Cxcr4 | Tff3 | ENSRNOP00000005143 | ENSRNOP00000060620 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). | 0.658 |
Fcgbp | Agr2 | ENSRNOP00000053950 | ENSRNOP00000068828 | Fc fragment of IgG-binding protein. | Anterior gradient 2 (Xenopus laevis) (Predicted), isoform CRA_a. | 0.613 |
Fcgbp | Muc13 | ENSRNOP00000053950 | ENSRNOP00000002444 | Fc fragment of IgG-binding protein. | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | 0.464 |
Fcgbp | Tff3 | ENSRNOP00000053950 | ENSRNOP00000060620 | Fc fragment of IgG-binding protein. | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). | 0.831 |
Havcr1 | Clu | ENSRNOP00000009573 | ENSRNOP00000072116 | Hepatitis A virus cellular receptor 1 homolog; May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity). | Clusterin alpha chain; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysos [...] | 0.743 |
Havcr1 | Cst3 | ENSRNOP00000009573 | ENSRNOP00000007175 | Hepatitis A virus cellular receptor 1 homolog; May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity). | Cystatin-C; As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Known to inhibit cathepsin B, H, and L; Belongs to the cystatin family. | 0.897 |
Havcr1 | Tff3 | ENSRNOP00000009573 | ENSRNOP00000060620 | Hepatitis A virus cellular receptor 1 homolog; May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity). | Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). | 0.646 |