node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SERP0113 | SERP0115 | SERP0113 | SERP0115 | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.778 |
SERP0113 | dnaX | SERP0113 | SERP0114 | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.839 |
SERP0113 | recR | SERP0113 | SERP0116 | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.784 |
SERP0115 | SERP0113 | SERP0115 | SERP0113 | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | 0.778 |
SERP0115 | dnaX | SERP0115 | SERP0114 | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.923 |
SERP0115 | recR | SERP0115 | SERP0116 | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.985 |
dnaA | pcrA | SERP2553 | SERP1443 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | ATP-dependent DNA helicase PcrA; Essential helicase; Belongs to the helicase family. UvrD subfamily. | 0.612 |
dnaA | recF | SERP2553 | SERP2550 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.760 |
dnaA | recR | SERP2553 | SERP0116 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.607 |
dnaX | SERP0113 | SERP0114 | SERP0113 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | 0.839 |
dnaX | SERP0115 | SERP0114 | SERP0115 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Conserved hypothetical protein TIGR00103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.923 |
dnaX | recO | SERP0114 | SERP1133 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA repair protein RecO family; Involved in DNA repair and RecF pathway recombination. | 0.473 |
dnaX | recR | SERP0114 | SERP0116 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.935 |
pcrA | dnaA | SERP1443 | SERP2553 | ATP-dependent DNA helicase PcrA; Essential helicase; Belongs to the helicase family. UvrD subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.612 |
pcrA | recF | SERP1443 | SERP2550 | ATP-dependent DNA helicase PcrA; Essential helicase; Belongs to the helicase family. UvrD subfamily. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.527 |
pcrA | recJ | SERP1443 | SERP1199 | ATP-dependent DNA helicase PcrA; Essential helicase; Belongs to the helicase family. UvrD subfamily. | single-stranded-DNA-specific exonuclease RecJ; Identified by similarity to EGAD:24228; match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.466 |
pcrA | recO | SERP1443 | SERP1133 | ATP-dependent DNA helicase PcrA; Essential helicase; Belongs to the helicase family. UvrD subfamily. | DNA repair protein RecO family; Involved in DNA repair and RecF pathway recombination. | 0.425 |
pcrA | recR | SERP1443 | SERP0116 | ATP-dependent DNA helicase PcrA; Essential helicase; Belongs to the helicase family. UvrD subfamily. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.661 |
recF | dnaA | SERP2550 | SERP2553 | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.760 |
recF | pcrA | SERP2550 | SERP1443 | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | ATP-dependent DNA helicase PcrA; Essential helicase; Belongs to the helicase family. UvrD subfamily. | 0.527 |